NVIDIA GeForce GT740
16 GB DDR3
Broken: 2.74 Release Candidate (Windows 64 Installer)
Short description of error
After turning off the setting "Load UI" in the user preferences, Blender will crash any saved file you click to open. I'm only certain this error occurs on my machine and with the Windows 64 bit Installer version of 2.74 RC. Sorry if this is not the area to report release candidate bugs, please correct me if it's not so I can post in the proper area next time.
Exact steps for others to reproduce the error
Go to File/User Preferences/ Select the File Tab
Uncheck "Load UI" setting and press "Save User Settings".
Save your current Blend file anywhere on your hardrive (any blend file and name it anything)
Click on the Blend file you saved to open it up
Blender crashes (note: this does not happen when loading the file from Blender's file manager)