Operating system: Windows-7-6.1.7601-SP1 64 Bits
Graphics card: GeForce GTX 970/PCIe/SSE2 NVIDIA Corporation 4.5.0 NVIDIA 436.48
Broken: version: 2.81 (sub 16), branch: master, commit date: 2019-11-15 16:32, hash: rBeba4a4bd73ba
Short description of error
after "load factory setting", go to Edit/Preferences. You can see that Blender become suddenly unresponsive.