Opened 12 of them in Gimp, PC did slow down a bit, Task manager froze for a while
Then it was fine after

Unfortunately I'm not sure how to get rid of the generated thumbnails
I can't test them in any Blender versions anymore.

I have a Ryzen 5 1600 6 cores and 12 threads
And 16 gig Ram DDR4

I've experimented and found that:

In 2.81 I loaded Factory Defaults, opened the folder and Blender crashed.

@Pablo Dobarro (pablodp606) This effects your Branch too.

Is this the issue with the Snake Hook slipping instead of holding onto the mesh?

Can confirm it works fine in RC3

I'm experiencing this too
in the 2.80 RC1

Don't really know who this bug effects but it does for me
Disabling "Cursor lock Adjust" seems to fix the problem though

Any update on this ?

Yeah I have this issue, it can be produced by Activating "Lock to Cursor " under the N menu
In 2.78 you could move the manipulators while having the Lock to Cursor
But 2.79, not able to move the manipulator anymore, instead the 3D Cursor is placed over it.