Hello, i want to subscribe to this issue because yeah it should definitely need to fix... with 1px radius, no AA, constant falloff brush paint chunks of 2/3/4 pixels, and for pixel art this is not good. Workaround at the moment exists, like addons, downscaling, or use external editors like Krita or Aseprite, but this should be a normal in blender too working on a single pixel, i think this issue don't need to have a low severity even if is not a breaking bug, but should gave more attention to fix in the upcoming releases, thanks dev for all the efforts!

Nvidia driver: 419.67 (Creator Ready Driver)