MS Windows 10 Fall Creator's Edition, Intel HD Graphics 4000 and NVIDIA GeForce8400GS
Broken: 2.79 5bd8ac9
Worked: Unknown/haven't seen it work
Short description of error
When switching a screen layout, the UI tends to switch to a prior scene.
Exact steps for others to reproduce the error
As saved, the attached .blend should load to “This little piggy went to market” in layout “3d View Full”.
Switch to layout “Default”. The scene should now switch to “This little piggy stayed home.”
If that doesn't repeat the error, just create a new .blend file, add a new scene, and switch to a different layout. This should bring you back to the original scene in the new layout.